| 摘要 |
FIELD: pharmaceutics.SUBSTANCE: series of inventions discloses pharmaceutical compositions for treating diseases or conditions caused by effect of expression or activity of PCSK9 containing an antibody which specifically binds to human proprotein of subtilisin/keksin convertase type 9 (PCSK9).EFFECT: use of compositions according to the series of inventions provides effective reduction of LDL-C level increasing HDL cholesterol level in serum, reduction of one or more of: levels of total cholesterol, ApoB levels, cholesterol not related to HDL-C, ratio of Apo-B/ApoA-1.19 cl, 6 dwg, 1 tbl, 6 ex |
