| 发明名称 |
PROCESS FOR PREPARING 3-FLUOROCEPHALOSPORINS |
| 摘要 |
<p>An ester of a 7-acylamido-3-fluoro-3-cephem-4-carboxylic acid is prepared by reacting a 3-sulfonate ester of an ester of a 7-acylamido-3-hydroxy-3-cephem-4-carboxylic acid in an inert solvent with an inorganic fluoride in the presence of an 18-crown-6 ether and at a temperature of from about -20 DEG C. to about +25 DEG C.</p> |
| 申请公布号 |
MW1074(A1) |
申请公布日期 |
1975.07.09 |
| 申请号 |
MW19740000010 |
申请日期 |
1974.03.20 |
| 申请人 |
ELI LILLY AND CY |
发明人 |
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| 分类号 |
A61K31/545;A61K31/546;A61P31/04;C07B61/00;C07D501/00;C07D501/04;C07D501/20;C07D501/59;(IPC1-7):07D/ |
主分类号 |
A61K31/545 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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