Preparation of phytone via the addition of dimethylketene to 4,8-dimethyl-12-oxotridecanal

摘要

Phytone is prepared from 4,8-dimethyl-12-oxotridecanal by conversion thereof into a dimethylketene- beta -lactone adduct, thermal decarboxylation of the adduct into 6,10,14-trimethyl-13-pentadecen-2-one and subsequent catalytic hydrogenation into phytone, a valuable intermediate in the synthesis of Vitamin E.