Des-asp{hu 1{b -thr{hu 8 {b angiotensin II as a specific inhibitor for the release of aldosterone

摘要

A new heptapeptide having specific inhibitory properties for the release of aldosterone from the adrenal cortex has been found. The new compound resembles angiotensin II except for the two terminal amino acids. The N-terminal amino acid (asparatic acid) is absent, while the C-terminus is occupied by L-threonine.