| 摘要 |
<p>A benzimidazole derivative of the formula (I), which has anti-inflammatory activity, and wherein R1 represents an ortho-hydroxyphenyl group, a para-chlorophenyl group or a para-fluorophenyl group; and R2 represents an alkyl group containing 2 to 4 carbon atoms, is produced, for example, by condensing a compound of the general formula (II), wherein R3 represents an ortho-hydroxypheny1 group, an orthoacyloxyphenyl group, an ortho-benzyloxyphenyl group, a parachlorobenzyl group or a para-fluorophenyl group, and X represents a halogen atom, an alkyl-sulphonyloxy group or an aryl-sulphonyl-oxy group, with an N-alkyl-piperazine of the general formula in which R2 has the above meaning.</p> |
