| 摘要 |
Porous tablets are produced by mixing the tablet components with a liquid solvent which is inert towards the components of the tablet and which freezes at a temperature from about -30 to +25 DEG C, the solvent constituting about 5 to 80% by weight of the total mixture, introducing the mixture into an inert cooling medium at a temperature low enough to solidify the solvent, pressing the mixture including the solidified solvent into tablets at a temperature below the freezing point of the solvent, and then evaporating the solvent from the tablets. Advantageously the solvent is water, cyclohexane, benzene and/or tert.-butanol, optionally containing alcohol. The tablets readily disintegrate in liquid. |
