| 发明名称 | DNA aptamers for promoting remyelination | ||
| 摘要 | Materials and methods related to using multimeric DNA aptamers to treat demyelinating diseases are provided herein. | ||
| 申请公布号 | US9481887(B2) | 申请公布日期 | 2016.11.01 |
| 申请号 | US201514837513 | 申请日期 | 2015.08.27 |
| 申请人 | Mayo Foundation for Medical Education and Resarch | 发明人 | Maher, III Louis J.;Rodriguez Moses |
| 分类号 | C07H21/02;C07H21/04;A61K31/70;C12N15/115;A61K38/17;A61K31/711;C12Q1/68 | 主分类号 | C07H21/02 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A method for promoting neuronal remyelination in the central nervous system of a subject in need thereof, comprising administering to the subject a pharmaceutical composition comprising a multimeric nucleic acid aptamer in an amount effective to promote remyelination in the central nervous system of the subject, wherein the nucleic acid aptamer comprises the sequence set forth in SEQ ID NO:17. | ||
| 地址 | Rochester MN US | ||