| 摘要 |
<p>The invention relates to 6-amino-2-penem-3-carboxylic acid compounds of the formula <IMAGE> (I) in which R1a denotes hydrogen or an amino protective group R1A and R1b represents hydrogen or an acyl radical Ac, or in which R1a and R1b conjointly form a bivalent amino protective group, R2 denotes hydroxyl or a radical R2A which, together with the carbonyl grouping -C(=0)-, forms a protected carboxyl group, and R3 represents hydrogen or an organic radical which is linked via a carbon atom to the ring carbon atom, and 1-oxides thereof, as well as salts of such compounds having salt-forming groups, which compounds possess antibiotic properties, processes for the manufacture of such compounds, and also pharmaceutical formulations containing compounds of the formula I with pharmacological properties, and the use thereof, either as antibiotics, preferably in the form of pharmaceutical formulations, or as intermediate products.</p> |
