NSAIDs-induced gastrointestinal mucosal disorder alleviator and manufacturing method thereof

摘要

A method of manufacturing a medical drug of alleviating damage of gastrointestinal mucosal induced by a non-steroidal anti-inflammatory drug, NSAID, the medical drug being able to induce anti-inflammatory effect of the NSAID and being able to alleviate damage induced by the NSAID includes dissolving trehalose and the NSAID into one or more solutions, so as to obtain an approximately homogenously-mixed liquid mixture of the trehalose and the NSAID; in which the liquid mixture contains an intermolecular compound with the trehalose and the NSAID; and drying the liquid mixture so as to obtain the medical drug.

主权项

1. A method of manufacturing a medical drug comprising an intermolecular compound of trehalose and a non-steroidal anti-inflammatory drug, NSAID, the method comprising:
dissolving the trehalose and the NSAID into one or more solutions to form an approximately homogenously-mixed liquid mixture of dissolved trehalose and dissolved NSAID, wherein the liquid mixture contains the intermolecular compound and a weight ratio of the trehalose to the NSAID in the liquid mixture is 1:1 to 30:1; and drying the liquid mixture so as to obtain the medical drug.