摘要 |
<p>P.C. 5874 - Canada Process for preparing 2-substituted-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido4,3-b!indoles of the formula: (I) and the pharmaceutically-acceptable salts thereof, wherein the hydrogen atoms in the 4a position and 9b position are in a trans relationship to each other and X and Y are the same or different and are each hydrogen or fluoro; R is a member selected from the group consisting of CH3, and wherein n is 3 or 4, m is 2 or 3, M is or ; and Z is a member selected from the group consisting of hydrogen, fluoro or methoxy and their use as tranquilizing agents.</p> |