发明名称 TRANS-5-ARYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO(4,3- B) INDOLES
摘要 <p>P.C. 5874 - Canada Process for preparing 2-substituted-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido4,3-b!indoles of the formula: (I) and the pharmaceutically-acceptable salts thereof, wherein the hydrogen atoms in the 4a position and 9b position are in a trans relationship to each other and X and Y are the same or different and are each hydrogen or fluoro; R is a member selected from the group consisting of CH3, and wherein n is 3 or 4, m is 2 or 3, M is or ; and Z is a member selected from the group consisting of hydrogen, fluoro or methoxy and their use as tranquilizing agents.</p>
申请公布号 CA1094071(A) 申请公布日期 1981.01.20
申请号 CA19780303710 申请日期 1978.05.19
申请人 PFIZER INC. 发明人 WELCH, WILLARD M., JR.
分类号 A61K31/435;A61K31/437;A61P25/18;A61P25/20;A61P25/22;C07D471/04;(IPC1-7):07D471/04 主分类号 A61K31/435
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