发明名称 |
SULPHONES (SULPHOXIDE) PHENOXY ALKANOLAMINES |
摘要 |
Propanolamine derivatives of the formula: <IMAGE> wherein R2 is CH3SO or CH3SO2; R3 is hydrogen, methyl or methoxy; or R2 and R3 are together -S(O)m(CH2)4-when S is attached at R2 or -(CH2)nS(O)m- when S is attached at R3(where m=1 or 2 and n=3 or 4); R4 is hydrogen or alkyl C1-4; Z is -(CH2)2- or <IMAGE> and their non-toxic salts. Processes for the preparation and pharmaceutical compositions thereof. The compounds exhibit both beta -adrenoreceptor antagonist activity and vasodilator activity and are indicated for use in the treatment of hypertension. |
申请公布号 |
AU7265581(A) |
申请公布日期 |
1982.01.14 |
申请号 |
AU19810072655 |
申请日期 |
1981.07.08 |
申请人 |
RECKITT & COLMAN PRODUCTS LTD. |
发明人 |
A.J.G. BAXTER;M. MYERS |
分类号 |
A61K31/135;A61P9/08;C07C67/00;C07C213/00;C07C217/30;C07C313/00;C07C315/04;C07C317/22;C07D335/06;C07D337/06;C07D337/08 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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