发明名称 5:Amino acyl 3:carbalkoxy amino di:benzo:azepine(s) - are cardiovascular agents free from stimulant or sedative side effects
摘要 <p>5-(Omega aminoacyl) -3-carbalkoxyamino -10,11-dihydro-5H-dibenzo (b,f) azepines of formula (I) and their salts are new (where n=1-3; R1 is 1-3C opt. branched alkyl; R2 and R3 is 1-3C alkyl or R2NR3 form a cyclic amino gp., such as piperidine, morpholine, N-1-3C alkyl piperazine, N-(beta hydroxyethyl piperazine or N-1,4-diazabicyclo -nonane, -decane or undecane). Used for treatment of cardiovascular disorders, such as arrhythmias. Lack of side effects, such as central stimulation or sedation.</p>
申请公布号 FR2493314(A1) 申请公布日期 1982.05.07
申请号 FR19800023564 申请日期 1980.11.05
申请人 INSTITUT FARMAKOLOGII AKADEMII 发明人 N. V. KAVERINA, V. V. LYSKOVTSEV, Z. P. SENOVA, A. N. GRITSENKO, Z. I. ERMAKOVA, A. P. SKOLDINOV, ERNST CARSTENS, HELMUT WUNDERLICH ET STARK ANDREAS;LYSKOVTSEV V V;SENOVA Z P;GRITSENKO A N;ERMAKOVA Z I;SKOLDINOV A P;CARSTENS ERNST;WUNDERLICH HELMUT;ANDREAS STARK
分类号 C07D223/22;C07D487/04;(IPC1-7):07D223/24;61K31/55 主分类号 C07D223/22
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