发明名称 |
5:Amino acyl 3:carbalkoxy amino di:benzo:azepine(s) - are cardiovascular agents free from stimulant or sedative side effects |
摘要 |
<p>5-(Omega aminoacyl) -3-carbalkoxyamino -10,11-dihydro-5H-dibenzo (b,f) azepines of formula (I) and their salts are new (where n=1-3; R1 is 1-3C opt. branched alkyl; R2 and R3 is 1-3C alkyl or R2NR3 form a cyclic amino gp., such as piperidine, morpholine, N-1-3C alkyl piperazine, N-(beta hydroxyethyl piperazine or N-1,4-diazabicyclo -nonane, -decane or undecane). Used for treatment of cardiovascular disorders, such as arrhythmias. Lack of side effects, such as central stimulation or sedation.</p> |
申请公布号 |
FR2493314(A1) |
申请公布日期 |
1982.05.07 |
申请号 |
FR19800023564 |
申请日期 |
1980.11.05 |
申请人 |
INSTITUT FARMAKOLOGII AKADEMII |
发明人 |
N. V. KAVERINA, V. V. LYSKOVTSEV, Z. P. SENOVA, A. N. GRITSENKO, Z. I. ERMAKOVA, A. P. SKOLDINOV, ERNST CARSTENS, HELMUT WUNDERLICH ET STARK ANDREAS;LYSKOVTSEV V V;SENOVA Z P;GRITSENKO A N;ERMAKOVA Z I;SKOLDINOV A P;CARSTENS ERNST;WUNDERLICH HELMUT;ANDREAS STARK |
分类号 |
C07D223/22;C07D487/04;(IPC1-7):07D223/24;61K31/55 |
主分类号 |
C07D223/22 |
代理机构 |
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代理人 |
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地址 |
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