发明名称 |
PROCEDIMIENTO PARA LA PREPARACION DE AMIDOACETAMIDO OXADETIA CEFALOSPORINAS 7-SUBSTITUIDAS |
摘要 |
<p>Antibacterial 7-substituted aminoacetamido oxadethiacephalosporins of the formula: <IMAGE> [wherein R is substituted amino, substituted phenyl, or 5- or 6-membered hetero ring; Ar is aryl; Y is hydrogen or methoxy; Het is 5- or 6-membered aromatic hetero ring; and Z is hydroxy or carboxy protecting group] preparable e.g. by acylation of 7 alpha -methoxy-7 beta -amino-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives, are highly active against gram-positive and gram-negative bacteria, especially those resistant to other cephalosporins and penicillins.</p> |
申请公布号 |
MX4451(E) |
申请公布日期 |
1982.05.11 |
申请号 |
MX19770006083U |
申请日期 |
1977.08.31 |
申请人 |
SHIONOGI & CO LTD |
发明人 |
NARISADA MASAYUKI;TSUJI TERUJI;YOSHIOKA MITSURU;MATSUMURA HIROMU;HAMASHIMA YOSHIO;HAYASHI SADAO;NAGATA WATARU |
分类号 |
C07D505/06;A61K31/535;A61K31/5365;A61P31/00;A61P31/04;C07D501/36;C07D505/00;C07D505/20;C07D505/22;(IPC1-7):07D501/34 |
主分类号 |
C07D505/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|