| 发明名称 | Tumour cytotoxic agent and methods thereof | ||
| 摘要 | The present invention discloses a novel antitumor agent which provides an antitumor activity based on metabolites with reduced side effects. Moreover, the antitumor agent is prepared starting with a highly safe bacterium used in food production, which is a probiotic lactic acid bacterium. | ||
| 申请公布号 | US9480721(B2) | 申请公布日期 | 2016.11.01 |
| 申请号 | US201013579936 | 申请日期 | 2010.11.29 |
| 申请人 | UNIVERSITI PUTRA MALAYSIA | 发明人 | Foo Hooi Ling;Loh Teck Chwen;Chuah Li Oon;Alitheen Noorjahan Banu;Abdul Rahim Raha |
| 分类号 | C12N1/20;C12R1/25;A61K35/74;A61K35/747;A23L1/30;A61K38/16 | 主分类号 | C12N1/20 |
| 代理机构 | Saliwanchik, Lloyd & Eisenschenk | 代理人 | Saliwanchik, Lloyd & Eisenschenk |
| 主权项 | 1. A method for treating a tumour wherein said method comprises administering, to a subject in need of such treatment, an anti-tumour agent that comprises a bacteria strain, and/or a metabolite from said bacteria strain, wherein said bacteria strain is selected from the group consisting of Lactobacillus plantarum I-UL4(NRRL B67067), TL1(NRRL B67068), RS5 (NRRL B67069), RG14 (NRRL B67071), RG11 (NRRL B67070) and RI11 (NRRL B67072) deposited at the Agricultural Research Culture Collection (NRRL), an International Deposit Authority recognized under the Budapest Treaty. | ||
| 地址 | Selangor MY | ||