发明名称 |
IMMUNOGLOBULIN CLEAVAGE FRAGMENTS AS DISEASE INDICATORS, REAGENTS FOR DETECTING SAME AND USES OF SUCH REAGENTS |
摘要 |
The invention relates to antibody reagents and use thereof to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions. |
申请公布号 |
EA025220(B1) |
申请公布日期 |
2016.12.30 |
申请号 |
EA20100070236 |
申请日期 |
2008.08.04 |
申请人 |
CENTOCOR ORTHO BIOTECH INC. |
发明人 |
JORDAN Robert;PETRONE Diane, D.;RYAN Mary |
分类号 |
C07K14/435;C07K16/18 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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