摘要 |
Pyridoindoles of the formula <IMAGE> in which R1 represents hydrogen or C1-C4-alkyl, which is optionally substituted by the radical <IMAGE> R2 and R3 represent H or form a bond, or R1 and R2 together represent O, -O-CH2-CH2-O- or -S-CH2-CH2-S-, R4 represents H or the <IMAGE> or R3 and R4 represent O, or R1 and R4 are members of an N-containing six-membered ring and R8 and R9 represent H or C1-C4-alkyl, or optionally form, with the N atom, a heterocyclic 5-membered or 6-membered ring, which can optionally also contain a further hetero-atom from the series comprising N, O or S, R5 represents H, C1-C4-alkyl or the group <IMAGE> or R5 and R3 form a bond, and R10 and R11 represent C1-C4-alkyl or are members of an N-containing 5-membered or 6-membered ring, R6 represents H or C1-C4-alkyl and R7 represents halogen, or acid addition salts thereof, which are active on the central nervous system. Novel intermediates are also shown. |