发明名称 |
OPTICALLY UNIFORM BETA-LACTAMS |
摘要 |
There is presented optically uniform beta -lactams of the formulae <IMAGE> wherein Z is a readily cleavable acyl group, R1 is amino or a group convertible into amino, R2 is hydrogen or a readily cleavable protecting group and R3 and R4 each are a lower hydrocarbon group which optionally contains oxygen and which is attached via a carbon atom, whereby these groups can also be joined with one another to form a ring, with the proviso that R1 is a readily cleavable acylamino when R2 is hydrogen, and the corresponding optical antipodes, their manufacture and use in the manufacture of antimicrobially-active beta -lactams as well as novel intermediates usable in their manufacture. |
申请公布号 |
NZ201660(A) |
申请公布日期 |
1986.01.24 |
申请号 |
NZ19820201660 |
申请日期 |
1982.08.20 |
申请人 |
F. HOFFMANN-LA ROCHE & CO AG. |
发明人 |
HUBSCHWERLEN, C.N.;SCHMID, G. |
分类号 |
C07D205/08;C07D205/085;C07D277/40;C07D317/28;C07D317/72;C07D403/04;C07D405/14;C07D493/14;(IPC1-7):C07D205/00;C07D405/00;C07C93/00;C07D317/00;C07D319/00 |
主分类号 |
C07D205/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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