摘要 |
<p>A benzoic acid derivative represented by the formula (I):
<CHEM>
wherein R1, R2, R3, R4 and R5 may be the same or different, each represents hydrogen, middle and lower alkyl, and cycloalkyl harring 3 - 7 atoms with proviso each can not be hydrogen simultaneously, and both neighbouring substituents may be combined with each other to form a ring having 5 to 12 carbon atoms, R6 represents hydroxyl, lower alkoxyl, a group of the formula -NR7 min R8 min , wherein R7 min and R8 min each represents hydrogen or lower alkyl, X represents a group of the formula
<CHEM>
wherein R7 and R8 represent hydrogen or lower alkyl. Furtheron a process to prepare this substances and a method to determ the type of leukemia is described. </p> |