摘要 |
<p>Steroid-21-phosphoric acids and pharmaceutically usable salts thereof of the formula III <IMAGE> III (in which U=H or CH3, V=H, OH, O or Hal; W=H or OH and Y=H or F) are obtained in a very pure state by reacting I <IMAGE> I (in which X=OH or Hal) with an organic phosphoric acid ester of the formula IVa or IVb <IMAGE> (in which Z=optionally substituted alkyl and R=alkyl). The compounds II <IMAGE> II obtained thereby is saponified to give III and the latter, if appropriate, is neutralized to give the salt. Compounds II are new.</p> |