| 摘要 |
<p>The invention discloses a series of difluoroketone, mono- di- and tri-peptide derivatives of formula Ia, Ib and Ic: -(Formula set out on pages following Examples) Ia -(Formula set out on pages following Examples) Ib -(Formula set out on pages following Examples) Ic - and salts thereof where appropriate, and wherein the radicals are defined hereafter in the specification. The derivatives are useful in inhibiting the action of human leukocyte elastase. There are also disclosed methods and intermediates for the manufacture of, and pharmaceutical compositions comprising, the said derivatives.</p> |
