PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6- (SUBSTITUTED)PICOLINATES 4--5--3--6-()-2-

摘要

4-Amino-5-fluoro-3-halo-6-(substituted)picolinates are conveniently prepared from 4,5,6-trichloropicolinonitrile by a series of steps involving fluorine exchange, amination, halogen exchange, halogenation, nitrile hydrolysis, esterification, and transition metal assisted coupling.