发明名称 MODIFIED HEM
摘要 PURPOSE:To obtain a modified hem having hydrophilic and hydrophobic nature, soluble in organic solvent and useful for the examination of lipoperoxide in blood, etc., by bonding carboxyl group of hem or hematin molecule with a polyalkylene glycol methyl ether. CONSTITUTION:Hem or hematin (e.g. protohem, protohematin, etc.) is made to react with a polyalkylene glycol methyl ether (e.g. polyethylene glycol methyl ether of formula) or its omega-amino derivative to obtain the objective modified hem. The compound can be used for the determination of peroxide in a fat- soluble substance extracted with an organic solvent.
申请公布号 JPS62181332(A) 申请公布日期 1987.08.08
申请号 JP19860023577 申请日期 1986.02.05
申请人 MIHAMA HISAHARU 发明人 INADA YUJI;TAKAHASHI KATSUNOBU
分类号 A61K35/18;A61K31/785;C07D487/22;C08G65/32;C12Q1/28 主分类号 A61K35/18
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