发明名称 |
PROCESS FOR PRODUCING DIHYDROPYRIDINE DERIVATIVES |
摘要 |
New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula <CHEM> wherein R<1> is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of lower alkyl, NO2, CN, CF3, Cl and Br; A is a straight or branched alkylene group with 2-5 carbon atoms; R<2> is <CHEM> wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R<3> and R<6> are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R<4> is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R<5> is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates. |
申请公布号 |
HU193786(B) |
申请公布日期 |
1987.11.30 |
申请号 |
HU19850002491 |
申请日期 |
1983.05.20 |
申请人 |
ACTIEBOLAGET HAESSLE,SE |
发明人 |
BERNTSSON,PEDER B.,SE;CARLSSON,STIG A.,SE;LJUNG,BENGT R.,SE |
分类号 |
A61K31/44;A61K31/455;A61K31/535;A61P9/06;A61P9/12;C07D211/90;C07D413/12 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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