发明名称 |
COMBINATION TREATMENT METHOD OF CD38-EXPRESSING TUMORS |
摘要 |
PROBLEM TO BE SOLVED: To provide a novel method for treatment of cancer using a combination therapy comprising an antibody that binds CD38, a corticosteroid and a non-corticosteroid chemotherapeutic agent.SOLUTION: A pharmaceutical composition is formed by combining i) a non-agonistic antibody which binds to CD38, ii) at least one glucocorticoid, and iii) at least one non-corticosteroid chemotherapeutic agent including thalidomide or a thalidomide analog, or a proteasome inhibitor.SELECTED DRAWING: None |
申请公布号 |
JP2016188228(A) |
申请公布日期 |
2016.11.04 |
申请号 |
JP20160111656 |
申请日期 |
2016.06.03 |
申请人 |
GENMAB AS |
发明人 |
WINKEL JAN VAN DE;PAUL PARREN;GRAUS YVO;OPRINS JUDITH;WEERS MICHEL DE;VUGT MARTINE VAN;OLE BAADSGAARD;STEEN LISBY |
分类号 |
A61K39/395;A61K31/198;A61K31/404;A61K31/454;A61K31/475;A61K31/573;A61K31/69;A61K31/704;A61K38/00;A61K38/21;A61K45/00;A61P35/00;A61P35/02;A61P43/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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