| 摘要 |
<p>A coagulation active complex of Factor VIII fragments is produced by causing a coagulation inactive FVIII heavy chain to react with a coagulation inactive FVIII light chain in the presence of a complex forming agent. Thus, FVIII-HC and FVIII-LC are converted to coagulation active FVIII complex in the presence of metal ions, such as Mn?2+, Ca2+ or Co2+¿ or a component of the prothrombin complex or a substance having reactivity to compounds containing the group -SH and/or -S-S.</p> |
