Expression of glycosylated human influenza hemagglutinin proteins

摘要

Glycosylated polypeptides corresponding to antigenic portions of mature human influenza hemagglutinin are microbially produced in S. cerevisiae. The glycosylated polypeptides are effective as vaccination agents, since the glycosylated polypeptides closely minic the naturally occurring mature influenza hemagglutinin which is also glycosylated.