| 发明名称 |
Cyclobutene-3,4-dione-intermediates and their use in the preparation of histamine h2-antagonists. |
| 摘要 |
The present invention relates to novel intermediates of the formula <CHEM> wherein R is lower alkyl or cyclohexyl, and X is hydroxy or a conventional leaving group, and the use thereof in a process for the preparation of certain histamine H2-antagonists. |
| 申请公布号 |
EP0294615(A1) |
申请公布日期 |
1988.12.14 |
| 申请号 |
EP19880107741 |
申请日期 |
1988.05.13 |
| 申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
DOUGLASS, JAMES L.;DEMOSTHENE, CLAUDE;FABRE, GUY |
| 分类号 |
A61K31/135;A61K;A61K31/40;A61K31/435;A61K31/445;A61P1/04;A61P43/00;B28C5/00;C04B28/36;C04B35/00;C07C;C07C67/00;C07C213/00;C07C221/00;C07C225/20;C07D211/14;C07D295/03;C07D295/08;C07D295/096;E04C1/40 |
主分类号 |
A61K31/135 |
| 代理机构 |
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