| 摘要 |
PROBLEM TO BE SOLVED: To provide preparation of (3aS,7aR)-hexahydroisobenzofuran-1(3H)-one by catalyzed biological resolution of dimethyl cyclohexane-1,2-dicarboxylate.SOLUTION: The present invention provides synthesis of (3aS,7aR)-hexahydroisobenzofuran-1(3H)-one, comprising enzymatic hydrolysis of dimethyl cyclohexane-1,2-dicarboxylate to form (1S,2R)-2-(methoxycarbonyl) cyclohexanecarboxylic acid. The enzyme can be from a non-mammalian source.SELECTED DRAWING: None |
