Fremgangsmåder og sammensætninger til methyleringsbaseret berigelse af føtal nukleinsyre fra en maternal prøve, som er egnet til ikke-invasive prænatale diagnoser

摘要

Provided are compositions and processes that utilize genomic regions differentially methylated between a mother and her fetus to separate, isolate or enrich fetal nucleic acid from a maternal sample. The compositions and processes described herein are useful for non-invasive prenatal diagnostics, including the detection of chromosomal aneuplodies.