| 摘要 |
In a liver function testing apparatus, light sources (11, 12) expose vital tissue (15) to first light of a wavelength absorbed by the specific dye closed into blood of the vital tissue to be taken in and removed by the liver and second light of a wavelength not absorbed by the dye. Optical pulses obtained from the vital tissue are received by a light receiving element (13) and first and second outputs therefrom are sampled by an A-D converter (30) to be converted into digital signals. Pulsation components of the outputs of the received light are detected by high-pass filters (51, 52) and amplifiers (53, 54). A coefficient of a linear regression expression between intensity values of the pulsation components, and a base value using the sampled first and second outputs of the received light are determined, whereby biocalibration is performed. A value correlated with specific dye concentration in the blood is calculated based on sampling outputs during a prescribed period and the determined coefficient base value after injection of the specific dye. Thus, a coefficient of a simulation function as a time function is obtained by using the method of least squares and a blood plasma disappearance rate and a retention rate are obtained on the basis of the coefficient of the simulation.
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