| 摘要 |
of the disclosure: There are provided thrombolytic agents suited for oral administeration. The agent comprises a proteolytic enzyme of subtilisin family, such as subtilisin BPN', subtilisin Carsberg, subtilisin amylosacchariticus, etc., produced by microorganisms belonging to genus Bacillus, such as Bacillus subtilis, Bacillus lincheniformia Bacillus amyloliquefaciens, etc. and, even when administered orally, exhibits thrombolytic activity.
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