发明名称 |
IGF-I fusion proteins; protection of IGF-I from degradation by host cell proteases; and processes for the production thereof |
摘要 |
IGF-I fused with a protective peptide, in which the protective peptide is a protein peptide and is used for the protection of IGF-I from degradation by protease in cells of E. coli is disclosed. Also disclosed are genes coding for the fused IGF-I's, plasmids containing the genes, and E. coli microorganisms transformed with the plasmids.
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申请公布号 |
US5019500(A) |
申请公布日期 |
1991.05.28 |
申请号 |
US19880217885 |
申请日期 |
1988.07.11 |
申请人 |
FUJISAWA PHARMACEUTICAL COMPANY, LTD. |
发明人 |
UEDA, IKUO;NIWA, MINEO;SAITO, YOSHIMASA;SATO, SUSUMU;ONO, HIROKI;KITAGUCHI, TADASHI |
分类号 |
C07K1/12;C07K14/00;C07K14/57;C07K14/575;C07K14/65;C07K19/00;C12N1/21;C12N15/09;C12N15/71;C12P21/02;C12R1/19 |
主分类号 |
C07K1/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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