| 发明名称 |
PEPTIDE-BASED INHIBITORS OF HIV REPLICATION |
| 摘要 |
2092075 9207871 PCTABS00013 Described herein are oligopeptides useful to inhibit HIV replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 5 .mu.m concentration, exhibits greater than 95 % inhibition of HIV replication, in a standard assay.
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| 申请公布号 |
CA2092075(A1) |
申请公布日期 |
1992.04.25 |
| 申请号 |
CA19912092075 |
申请日期 |
1991.10.23 |
| 申请人 |
ALLELIX BIOPHARMACEUTICALS INC. |
发明人 |
SUMNER-SMITH, MARTIN;BARNETT, RICHARD W.;REID, LORNE S.;SONENBERG, NAHUM |
| 分类号 |
A61K38/00;A61K38/08;A61P31/12;C07K7/06;C07K7/08;C07K14/155;(IPC1-7):C07K7/06;A61K38/04 |
主分类号 |
A61K38/00 |
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