发明名称 N-substituted-4-pyrimidinamines and pyrimidinediamines
摘要 This invention relates to N-heteroaryl-4-pyrimidinamines of the formula <IMAGE> where R1 is hydrogen, loweralkyl, aryl, or arylloweralkyl; R2 and R3 are independently hydrogen or loweralkyl, or R2 and R3 taken together are aryl; R4 and R5 are independently hydrogen or loweralkyl, or R4 and R5 taken together are aryl; X is hydrogen, halogen, cyano, nitro, amino, loweralkyl, loweralkoxy, trifluoromethyl or <IMAGE> where Y is hydrogen, halogen or loweralkyl; m is an integer of 1 to 3; and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometrical and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as memory enhancing agents and as analgesic agents.
申请公布号 US5179204(A) 申请公布日期 1993.01.12
申请号 US19900584554 申请日期 1990.09.18
申请人 HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED 发明人 EFFLAND, RICHARD C.;KLEIN, JOSEPH T.;DAVIS, LARRY;OLSEN, GORDON E.
分类号 C07D403/12;C07D403/14 主分类号 C07D403/12
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