INHIBITOR OF SPC/Fyn/Rho KINASE SIGNAL TRANSMISSION PATH

摘要

PROBLEM TO BE SOLVED: To provide an inhibitor of a sphingosylphosphorylcholine/Fyn/Rho kinase signal transmission path, or an inhibitor of vasospasm dependent on the sphingosylphosphorylcholine/Fyn/Rho kinase signal transmission path.SOLUTION: An inhibitor of a sphingosylphosphorylcholine/Fyn/Rho kinase signal transmission path which has a calpain inhibitor as an active ingredient, or an inhibitor of vasospasm dependent on the sphingosylphosphorylcholine/Fyn/Rho kinase signal transmission path which has a calpain inhibitor as an active ingredient is produced. It is preferable that the calpain inhibitor is 2-mercapto-3-(4-iodophenyl) propanoic acid.SELECTED DRAWING: Figure 4