| 摘要 |
A method of biospecifically capturing biological particles on a porous matrix, comprising bringing the particle suspended in an aqueous liquid into contact with the pore system of a porous matrix which is insoluble in water and the pore surfaces of which have bound thereon a bioaffinity counterpart to the particle to be captured, under conditions which enable desired particles to bind to the pore surfaces of the porous matrix via the bioaffinity counterpart. The method is characterized in that the matrix is elastically compressible, self-supporting and has capillaries of such pore dimensions as to enable the particles to pass through the matrix. The matrix is preferably brought into contact with the liquid in a compressed state and is allowed to relax after contact with the liquid. Alternatively, the matrix is subjected to cyclic compression-relaxation, preferably several times, during the incubation phase. |
