| 摘要 |
This invention is directed towards the production of a bioabsorbable glass-polymer alloy comprising a bioabsorbable glass and a bioabsorbable polymer, said glass having a working temperature below about 350 DEG C., a transition temperature no higher than about 250 DEG C., and which exhibits a dissolution weight loss rate which is similar to the rate at which a bioabsorbable polymer is absorbed by the body. Such exemplary bioabsorbable polymers include poly(lactic) acid, poly(glycolic) acid, poly(dioxanone), polyethylene terephthalate, polyethylene oxide poly(caprolactone), copolymers of lactic acid and glycolic acid, and mixtures thereof. The glass disclosed herein consists essentially, expressed in terms of weight percent on the oxide basis, of at least 85% total of 30-55% P2O5, 12-35% ZnO, 10-30% Cl, and 15-40% R2O, wherein R2O consists of at least one alkali metal oxide in the indicated proportions selected from the group consisting 5-25% Na2O, 0-25% K2O, and 0-7% Li2O, and up to 15% total optional ingredients in the indicated proportions selected from the group consisting of 0-10% CaO, 0-10% MgO, 0-10% MnO, 0-10% B2O3, 0-5% Al2O3, 0-10% Fe2O3 and 0-5% F.
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