| 摘要 |
The invention pertains to a method for purifying a first fatty acid, preferably polyunsaturated, based on an initial mixture further comprising at least one second fatty acid, optionally a third fatty acid, and optionally a fourth fatty acid, the method comprising: a first step of liquid-phase chromatographic purification, based on the initial mixture, carried out in a first chromatographic separation unit, making it possible to retrieve both a first flow enriched with the first fatty acid and a flow enriched with the second fatty acid; optionally, a second step of liquid-phase chromatographic purification, based on the first flow enriched with the first fatty acid, carried out in a second chromatographic separation unit, making it possible to retrieve both a second flow enriched with the first fatty acid and a flow enriched with the third fatty acid; optionally, a third step of liquid-phase chromatographic separation, based on the third flow enriched with the first fatty acid, carried out in a third chromatographic separation unit, making it possible to retrieve both a third flow enriched with the first fatty acid and a flow enriched with a fourth fatty acid; at least one of the first chromatographic separation unit, the second chromatographic separation unit and the third chromatographic separation unit being a static-bed, single-column chromatographic separation unit with steady-state recirculation. |
