| 摘要 |
PCT No. PCT/GB93/01586 Sec. 371 Date May 9, 1995 Sec. 102(e) Date May 9, 1995 PCT Filed Jul. 27, 1993 PCT Pub. No. WO94/02147 PCT Pub. Date Feb. 3, 1994A water-dispersible tablet comprising 2-amino-2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidine together with a swellable clay disintegrating agent and a further disintegrating agent. The tablet can be used in the treatment of neurodegenerative and other neurological disorders of the central nervous system, the etiology of which includes excessive release of neurotransmitter glutamate, including Alzheimer's disease, cerebral ischemic damage, chronic pain and epilepsy. |
