发明名称 |
Oral administration of antigens |
摘要 |
An oral vaccine formulation is provided for stimulation of an immune response in gut-associated lymphoid tissues. The formulation comprises an enzymatically degradable antigen in a hydrogel matrix. In ruminant species, the vaccine formulation, upon oral administration, is formed to pass through the rumen without substantial hydration and then into the post-ruminal portion of the digestive tract where the antigen is released for contact with the gut-associated lymphoid tissue. |
申请公布号 |
AU4671493(A) |
申请公布日期 |
1994.02.14 |
申请号 |
AU19930046714 |
申请日期 |
1993.07.09 |
申请人 |
PURDUE RESEARCH FOUNDATION |
发明人 |
BOWERSOCK TERRY L;SHALABY WALEED SHALABY WAHBA;BLEVINS WILLIAM EARL;LEVY MICHEL;PARK KINAM |
分类号 |
A61K9/00;A61K9/16;A61K9/22 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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