| 摘要 |
<p>Benzylidene derivatives having anti-inflammatory activities, have the following formula I: <CHEM> wherein A is -CH2- or -CH2CH2-; B is a bond or -CH2-, -CHOH-, -CO-, -O-, or A and B may taken together form -CH=CH-; D is >N- or >CH-; R<1> and R<2> each independently is hydrogen, lower alkyl or lower alkoxy; R<3> is hydrogen, lower alkyl, cycloalkyl, lower alkoxy, arylalkyloxy, heteroarylalkyloxy, lower alkylcarbonyl, arylcarbonyl, substituted or unsubstituted carbamoyl, or a group of the formula: -(CH2)n-R<4> wherein R<4> is hydrogen, hydroxy, substituted or unsubstituted amino, aryl, heteroaryl, hydroxycarbonyl or lower alkyloxycarbonyl; n is an integer of 0 - 3.</p> |
