发明名称 Method and composition for increased skin concentration of active agents by iontophoresis
摘要 The invention discloses methods and compositions for enhanced skin concentration of iontophoretic delivered active agents. The compositions are pharmaceutically acceptable compositions for iontophoretic delivery which comprise a skin concentration enhancing amount of a vasoconstrictor and active agent. Methods comprise adding a skin concentration enhancing amount of a vasoconstrictor to an active agent and delivering by iontophoresis.
申请公布号 US5334138(A) 申请公布日期 1994.08.02
申请号 US19910653204 申请日期 1991.02.08
申请人 NORTH CAROLINA STATE UNIVERSITY;BECTON DICKINSON AND COMPANY 发明人 SAGE, JR., BURTON H.;RIVIERE, JIM E.
分类号 A01N1/00;A61K9/00;A61K31/135;A61K31/165;A61K31/22;A61K31/415;A61K31/445;A61K31/47;A61K31/505;A61K45/00;A61K45/06;A61K47/22;A61N1/30;A61P9/00;A61P9/08;A61P43/00;(IPC1-7):A61N1/30 主分类号 A01N1/00
代理机构 代理人
主权项
地址