发明名称 |
Method and composition for increased skin concentration of active agents by iontophoresis |
摘要 |
The invention discloses methods and compositions for enhanced skin concentration of iontophoretic delivered active agents. The compositions are pharmaceutically acceptable compositions for iontophoretic delivery which comprise a skin concentration enhancing amount of a vasoconstrictor and active agent. Methods comprise adding a skin concentration enhancing amount of a vasoconstrictor to an active agent and delivering by iontophoresis.
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申请公布号 |
US5334138(A) |
申请公布日期 |
1994.08.02 |
申请号 |
US19910653204 |
申请日期 |
1991.02.08 |
申请人 |
NORTH CAROLINA STATE UNIVERSITY;BECTON DICKINSON AND COMPANY |
发明人 |
SAGE, JR., BURTON H.;RIVIERE, JIM E. |
分类号 |
A01N1/00;A61K9/00;A61K31/135;A61K31/165;A61K31/22;A61K31/415;A61K31/445;A61K31/47;A61K31/505;A61K45/00;A61K45/06;A61K47/22;A61N1/30;A61P9/00;A61P9/08;A61P43/00;(IPC1-7):A61N1/30 |
主分类号 |
A01N1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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