摘要 |
A method of separating a small number of target cells from a heterogeneous cell suspension in a liquid medium by repeatedly passing through the cell suspension at their gravitationally driven settling or rising rate therein particles having attached to the exterior thereof multiple target cell-specific binding species; and separating target cells bound to the particles from the heterogeneous cell suspension. The method can further include the step of releasing the target cells from the particles. The heterogeneous cell suspension is preferably a suspension of maternal blood cells and the target cells are preferably fetal cells. |