Monitoring device for management of insulin delivery

摘要

Monitoring system and method for use with diabetic treatment management. The system comprises: a communication interface configured to permit access to stored raw log data, obtained over a certain time, being indicative of glucose measurements, meals consumed and insulin delivery; and a control unit comprising an unsupervised learning controller configured to receive and process said raw log data and determine at least one global insulin pump setting of basal rate, correction factor, carbohydrate ratio and insulin activity curve parameters. The system may comprise a processing unit comprising a first processor for processing measured data indicative of blood glucose level and generating first processed data, a second processor comprising at least one fuzzy logic module which receives input parameters corresponding to the measured data, the first processed data and a reference data, and processes the data to produce a qualitative output parameter to determine whether any treatment parameter should be modified.

主权项

1. A monitoring system for use with disease treatment management, the monitoring system comprising:
a communication interface to permit input of raw log data, said raw log data being indicative of data obtained over a certain time and including time spaced data points of glucose measurements, meals consumed and insulin delivery; a control unit configured for receiving and processing said raw log data, the control unit comprising:
a sectioning module configured to section the raw log data within at least one time window; the sectioned time window being at least one of Basal data Section (BaS), Meals data Section (MS) and Bolus data Section (BS), each sectioned time window having a starting point and having an end point such that the BaS is selected outside an effect window of either a meal event or an insulin bolus, the MS is selected at a predetermined time ahead of a meal data point, and the starting point of the BS is selected as one of the following: (a) the end point of the MS or the BaS, and (b) an insulin bolus data point which is outside the MS; the end point of the BS being selected as one of the following, (i) the starting point of the MS or BaS and (ii) a predetermined time ahead of the insulin bolus data point without any intervening insulin bolus;an unsupervised learning controller configured and operable to determine an informative data piece from a residual log data portion of said raw log data, analyze said informative data piece and select a sectioned time window for calculation of an individualized patient's profile related data comprising at least one of drug injection setting of basal insulin treatment, correction factor (CF), carbohydrate ratio (CR) and activity curve parameters of said drug, wherein calculation of the basal insulin treatment is based on BaS, calculation of at least one of the drug activity curve parameters, correction factor (CF) and carbohydrate ratio (CR) is based on MS, and calculation of the correction factor (CF) or the drug activity curve parameters is based on BS; andan output module for generating treatment data which is indicative of the individualized patient's profile related data and is configured for at least one of the following: for operating a drug injection device, and for presentation on user interface.