发明名称 Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
摘要 Dithiocarboxylates, and in particular, dithiocarbamates, block the induced expression of the endothelial cell surface adhesion molecule VCAM-1, and are therefor useful in the treatment of cardiovascular disease, including atherosclerosis, post-angioplasty restenosis, coronary artery diseases, and angina, as well as noncardiovascular inflammatory diseases that are mediated by VCAM-1.
申请公布号 US5380747(A) 申请公布日期 1995.01.10
申请号 US19920969934 申请日期 1992.10.30
申请人 EMORY UNIVERSITY 发明人 MEDFORD, RUSSELL M.;OFFERMANN, MARGARET K.;ALEXANDER, R. WAYNE
分类号 C07D295/10;A61K31/145;A61K31/185;A61K31/198;A61K31/27;A61K31/325;A61K31/40;A61K31/445;A61K45/06;A61P9/00;A61P9/02;A61P9/08;A61P9/10;A61P29/00;C07C333/04;C07C333/06;G01N33/68;(IPC1-7):A61K31/40 主分类号 C07D295/10
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