| 发明名称 |
Platelet activating factor antagonists |
| 摘要 |
PCT No. PCT/US92/01195 Sec. 371 Date Jul. 7, 1993 Sec. 102(e) Date Jul. 7, 1993 PCT Filed Feb. 14, 1992.Indole compounds substituted at the 1- or 3-position by a (pyrid-3-yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl)dithiolan-4-oyl)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including septic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.
|
| 申请公布号 |
US5382670(A) |
申请公布日期 |
1995.01.17 |
| 申请号 |
US19930084257 |
申请日期 |
1993.07.07 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
SUMMERS, JAMES B.;SHEPPARD, GEORGE S.;PHILLIPS, JAMES G.;PIREH, DAISY;STEINMAN, DOUGLAS H.;MAY, PAUL D.;GUINN, DENISE E.;HEYMAN, H. ROBIN;CARRERA, JR., GEORGE M.;DAVIDSEN, STEVEN K. |
| 分类号 |
A61K31/44;A61K31/4427;A61K31/4433;A61P7/02;A61P11/00;A61P29/00;C07D401/14;C07D403/14;C07D409/14;C07D417/14;(IPC1-7):C07D213/04;C07D209/04;C07D277/04 |
主分类号 |
A61K31/44 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
