| 发明名称 |
Method of inhibiting thrombus formation by the 7E3 monoclonal antibody |
| 摘要 |
The monoclonal antibody designate 7E3 blocks the interaction of fibrinogen with platelets, prevents thrombus formation, reacts with both human and dog platelets and fails to react with thrombasthenic human platelets or human platelets whose GPIIb/IIIa complex is dissociated with EDTA. A fragment of the 7E3 antibody can prevent occlusion by thrombus in the circulatory system.
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| 申请公布号 |
US5387413(A) |
申请公布日期 |
1995.02.07 |
| 申请号 |
US19910767114 |
申请日期 |
1991.09.27 |
| 申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
COLLER, BARRY S. |
| 分类号 |
A61K38/00;C07K16/28;C12P21/08;(IPC1-7):A61K39/395;C07K16/00 |
主分类号 |
A61K38/00 |
| 代理机构 |
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| 主权项 |
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| 地址 |
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