发明名称 SUBSTITUTED-HEXAHYDROBENZO A PHENANTHRIDINES
摘要 <p>Trans-hexahydrobenzo[a]phenanthridine of the formula <IMAGE> wherein R is hydrogen or C1-C4 alkyl; R1 is hydrogen or a phenoxy protecting group, X is fluoro, chloro, bromo, iodo or a group of the formula-OR5, and R2, R3, and R4 are independently selected from the group consisting of hydrogen, C1-C4 alkyl, phenyl, fluoro, chloro, bromo, iodo, or a group -OR1 provided that at least one of R2, R3, and R4 are other than hydrogen, are novel ligands for dopamine receptors.</p>
申请公布号 EP0644877(A1) 申请公布日期 1995.03.29
申请号 EP19930914148 申请日期 1993.05.26
申请人 PURDUE RESEARCH FOUNDATION;THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 发明人 NICHOLS, DAVID E.;MAILMAN, RICHARD B.
分类号 A61K31/44;A61K31/47;A61K31/473;A61P9/12;A61P25/00;A61P25/16;A61P25/18;A61P43/00;C07D221/18;(IPC1-7):C07D221/18 主分类号 A61K31/44
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