| 摘要 |
PCT No. PCT/GB93/02006 Sec. 371 Date May 19, 1995 Sec. 102(e) Date May 19, 1995 PCT Filed Aug. 27, 1993 PCT Pub. No. WO94/07837 PCT Pub. Date Apr. 14, 1994Disclosed are certain novel polyunsaturated dioic acids having between 8 and 16 carbon atoms (inclusive), excluding those compounds in the group consisting of: 2,5 octadienedioic acid; 1,7 octadienedioic acid; 2,4,6 octatrienedioic acid; and 1,3,5,7 nonatetraenedioic acid; 2,5,8 decatrienedioic acid; 3,6 dodecadienedioic acid; 3,13 hexadecadienedioic acid. Also disclosed are pharmaceutical or cosmetic compositions comprising unsaturated dioic acids and certain of their derivatives. Also disclosed are methods of treating human skin and a method of preparing unsaturated dioic acids. |
