发明名称 |
NOVEL COMPOUND HAVING PLATELET AGGREGATION INHIBITOR EFFECT |
摘要 |
<p> <CHEM> A compound represented by general formula (I) and having a platelet aggregation inhibitor effect and pharmacologically acceptable salt and solvate thereof, wherein A, B and C represent each CH2 or C=O; X and Y are different from each other and represent CH or N; D represents -(CH2)k- or -(CH2)m-CO-, wherein k represents an integer of 1 to 4, and m represents an integer of 0 to 3; E represents group (II) or (III), wherein n represents an integer of 1 to 3, Z represents -W-(CH2)p-COOR<3>, W represents -O- or a bond, p represents an integer of 1 to 4, and R<3> represents hydrogen, lower alkyl or an ester residue eliminable under physiological conditions; R<1> represents hydrogen or lower alkyl; and R<2> represents hydrogen or lower alkyl.</p> |
申请公布号 |
EP0721941(A1) |
申请公布日期 |
1996.07.17 |
申请号 |
EP19950925137 |
申请日期 |
1995.07.17 |
申请人 |
MEIJI SEIKA KABUSHIKI KAISHA |
发明人 |
KATANO, KIYOAKI;OHUCHI, SHOKICHI;MIURA, TOMOAKI;SHITARA, EIKI;SHIMIZU, MASARO;YAEGASHI, KAZUE;OHKURA, NAOTO;ISOMURA, YASUKO;IIDA, HIROYUKI;ISHIKAWA, MIDORI;ASAI, KENJI;HATSUSHIBA, EMIKO |
分类号 |
A61K31/445;A61K31/495;C07D211/58;C07D401/04;C07D401/06;C07D401/14;C07D405/14;(IPC1-7):C07D211/58 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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